
Studies that provided the high-dose (more than 2.7 g/day of EPA and
DHA)
n-3 PUFAs showed greater improvements in morning stiffness and
number
of painful and/or joints compared to low-dose n-3 PUFA.
• Patients receiving n-3 PUFAs EPA/DHA fared better than placebo for morning stiffness.
• Patients receiving n-3 PUFAs EPA/DHA fared better than placebo for number of painful
and/or tender joints.
• Patients receiving n-3 PUFAs EPA/DHA fared better than placebo for reduced NSAID
consumption.

The
results of the present meta-analysis support the hypothesis that n-3 PUFAs EPA/DHA supplementation improves pain outcomes after three
months.Journal of Pain - May 2007, 129(1-2), pp.210-223.
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